Radical Cystectomy

Description of Procedure

 

A radical cystectomy is a major surgery used to treat high-risk bladder cancers, usually muscle invasive bladder cancer. In select circumstances it may be used for superficial but high-risk bladder cancer not amenable to other types of treatment.

 

In some circumstances, patients will have an increased chance of cure if they receive a course of chemotherapy prior to the surgery (neoadjuvant chemotherapy), in other situation the chemotherapy is best given after surgery (adjuvant chemotherapy). Some patients do not require any chemotherapy at all. This will depend on your particular circumstances.

 

Here is what to expect once a decision to remove the bladder is made. Print this out to you can check the items off as you proceed through the process.

 

Preparation for Surgery

 

There is a lot of preparation before this surgery to make sure the surgery and your recovery are as good as possible. YOU MUST BE AN ACTIVE PARTICIPANT TO ENSURE THE BEST POSSIBLE RESULT. Read the information you are given and follow the instructions. Download and read this booklet!

 

Radical Cystectomy Patient Booklet ERAS v. July 2016

 

You can watch a video on the ERAS process here.

 

 Pre-operative Imaging

 

CT Scan - chest, abdomen and pelvis. This has typically been done before the decision to proceed with surgery has been made.

 

☐ Stoma Marking

 

APPOINTMENT: ___________________________________________________________

Location: Richmond Hospital North Tower 4th Floor

 

Your appointment will be arranged for you at the hospital with the stoma nurse. No matter what type of urinary reconstruction you are undergoing (continenent bladder substitute/Studer pouch, catheterizable pouch or ileal conduit/stoma) you will need to see the stoma nurse for marking. The reason is that an ileal conduit is the default type of urinary reconstruction if a Studer pouch or other type of diversion is not possible for technical reasons that are discovered during the surgery. A mark will be placed in the lower abdomen on the RIGHT side and covered with a tape so the mark does not come off.

 

Making Contact with Ostomy Supply Distributor

 

Following surgery you will have assistance by home care nursing for the first couple of months with changing of the stoma appliance. The appliance needs to be changed every 3-5 days. Fit of the appliance is very important in ensuring that the stoma and skin remain healthy and that leakage does not occur. Having a trained professional assess your particular situation to obtain the best possible fit is very important. There are many different types of appliances to select from and purchasing supplies without the assessment may not provide the best results (and may cost more because of more frequent replacement).

 

You will receive a referral to see an ostomy specialist. We have been working with Lauren Wolfe and her team for years and like the Nightingale group.  They can assist with obtaining insurance coverage whenever possible and ensuring you get the best value. Ostomy supplies may be eligible for some coverage under Pharmacare - the level will depend on your financial situation.

 

☐ Nurse Continence Advisor (Optional)

 

APPOINTMENT: ___________________________________________________________

Location: Richmond Hospital Westminister Health Centre (North-most part of the hospital) in Ambulatory Care. Corey Knott is the NCA.

 

You do NOT need to see the nurse continence advisor (NCA) if you have decided to have an ileal conduit or stoma procedure. If a decision to have any sort of urinary reconstruction that may require catheterization (e.g. Studer pouch, Mitrofanoff, other) you will need to see our NCA. She will teach you how to catheterize yourself. She will also see you after surgery to ensure you are comfortable with the process of clean intermittent catheterization (CIC).

 

☐ Pre-Admission Clinic: Anesthesia and Internal Medicine 

 

APPOINTMENT: ___________________________________________________________

Location: Richmond Hospital Pre-operative Assessment Clinic Main Floor North Tower near Radiology

 

Anesthesia will meet with you a couple of weeks prior to the surgery to ensure that your condition is optimized and to make sure your journey through the operating room is smooth and that your pain is well controlled after surgery. You will have your blood testing done at that time. They will discuss:

  • Any additional testing necessary to assess your status. For example, specialized They will discuss what is involved with the process of going under anesthesia
  • What is involved with a general anesthetic. Use of an epidural
  • Medications. What to continue, stop or any changes

Many patients will also be seen by someone from anesthesia to ensure that your general medical management is optimized on a long term basis and for other specialized testing (e.g. heart or lung function tests).

 

☐ For You to Do

 

Your participation is just as important as that of the doctors, nurses and other health professionals involved in your care. Richmond Hospital uses the Enhanced Recovery After Surgery Program (ERAS) to achieve these results.  Ensure you have read the patient information booklet on Radical Cystectomy (link is also at the start).

 

  • Stop smoking see your family physician for help
  • Exercise: be in the best shape you can be. Even walking 30 minutes a day will help recovery
  • Diet: eat a healthy diet. 'Carbohydrate load' an oral nutritional supplement such as 'Boost', 'Ensure' or similar for 1-2 days prior to surgery
  • Chewing gum: bring sugar free chewing gum to the hosptial - chewing gum starting from the night of surgery will help recovery of bowel function
  • Wash: reduce the chance of infection by washing with soap containing chlorhexiding starting  a couple of days prior to surgery. Ask your pharmacist - it is available over the counter without prescription. Examples include Stanhexidine solution, Stanley Chlorhexidine. Shower the night prior to surgery and then wipe down with Chlorhexidine gluconate 2% wipes (SAGE- Antiseptic Body Cleanser).
  • Sleep: get a good night of rest. Contact your family physician if you need sleeping pills.
  • Waterproof mattress protector. Accidents with leakage of urine are pretty common after surgery (but will greatly improve over time. 
  • Medic Alert Bracelet with "Cystectomy, Bladder Substitute" if you have a Studer Pouch or "Cystectomy with Ileal Conduit" if you have a condui
  • Home preparation: think about having your house in order and fridge stocked for when you come home. 

 

Surgery

 

APPOINTMENT: ___________________________________________________________

Location: Richmond Hospital Admission; You will be called the day prior to surgery for you check in time.

 

YOU WILL RECEIVE VERY SPECIFIC INSTRUCTIONS FROM THE PRE-ADMISSION CLINIC: 

 

☐ Medications to take the night prior to surgery
☐ Fasting

  • NEVER EAT ANY SOLID FOOD OR DRINK ANY FLUID THAT IS NOT CLEAR AFTER MIDNIGHT
    • You may be asked to drink 1 cup of apple juice the morning of your surgery before coming into hospital
    • Common mistakes are to eat breakfast, drink coffee or tea, drink non-clear fluids such as orange juice - all of these are strictly prohibited prior to surgery. Failure to follow tese instructions may result in cancellation of your surgery.

 

How the Surgery is Done

 

After you go to sleep, the surgery takes between 3-5 hours and is done under a general anesthetic. No matter which type of reconstruction you receive, the cut in the skin is in the lower abdomen below the belly button. The surgery has 2 parts.

 

PART ONE: radical cystectomy and pelvic lymph node dissection. Radical cystectomy means that the bladder and adjacent organs are removed in order to maximize the chances of cure. The exact details of the surgery may vary based on your specific circumstances. Here is what is removed as part of a radical cystectomy:

 

  1. Bladder
  2. Adjacent organs: those structures which are in direct contact with the bladder
    1. Males: prostate, sometimes the entire urethra
    2. Females: uterus (to include the cervix and often with the ovaries) and part of the anterior (front) of the vaginal wall
  3. Pelvic lymph nodes

 

PART TWO: reconstruction of urinary tract. After the bladder is removed, the urine needs to go somewhere. There are many different forms of reconstruction but the 2 most commonly used approaches are:

 

  1. Ileal conduit – this requires use of a stoma appliance
  2. Orthotopic neobladder – usually the Studer pouch

 

Ileal Conduit

 

This is the simplest form of urinary reconstruction. The ureters from the kidney are attached to a segement of bowel (specifically, the end of the small bowel - the ilium). That segment of bowel forms the conduit. Continuity in the bowel is re-established by sewing or stapling the cut ends back together. It is the most reliable and least trouble-free type of urinary reconstruction but does require lifelong use of a stoma bag.

 

 

Ileal conduit small

 


The ureters are 'plugged in' to the conduit by seweing them in. Stents (essentially specialized straws/tubes) are placed through anasstomosis (the 'joint') to allow them to heal. The stents are usually removed about 1 week after surgery. Monitoring to ensure that the anastomosis is functioning properly is done with a periodic ultrasound or CT scan. The urine drains continually into a stoma bag which is then emptied through a valve into a container or toilet several times a day. There are many different types of this appliances to match your body shape. An ostomy nurse will help you find one that fits you best. The appliance is then changed by the patient every 5 days or so. This entails pulling the old appliance off, cleaning the skin and placing a new pouch over the stoma. People with ileal conduits and stomas can particiapte in any sort of activity though need to avoid contact sports.

 

About 1 in 10 people who have an ileal conduit need to have additional surgery for revision. Things like herniation around the stoma (parastomal hernia), scarring where the ureters plug into the conduit (strictures of the anastomosis) or scarring where the conduit exits the body (stomal stenosis) are all potential problems that may arise. Having said that, an ileal conduit is the most trouble-free sort of reconstruction and should strongly be considered if you are very averse to needing additional surgery, higher maintenance or the potential for lifelong catheterization. All types of urinary reconstruction require some maintenance, just like a car. The ileal conduit is the reconstructive version of a Toyota or Honda.

 

 

Studer Pouch

 

A Studer pouch is one type of a bladder substitute. It is one of the most reliable and commonly performed types of bladder substitutes - also known as 'orthotopic continent bladder replacements'. It allows the patient to empty the bladder through the urethra - that is, it does not require any outside appliances or drainage bags. Aside from the surgical scars, your outward appearance will be the same as it is now.

 

A Studer pouch is NOT a 'new bladder' and it is critical to understand the important ways in which it differs from a bladder.  Not everyone is a candidate for this sort of reconstruction. To be a candidtate you must fulfill every single one of the following requirements:

 

  1. Agree to lifelong monitoring and followup
  2. Be willing to perform lifelong self catheterization several times per day if it is necessary (see 'Inability to Urinate' below)
  3. Have good hand dexterity
  4. Have good kidney function
  5. Have good liver function
  6. NOT require proton pump inhibitors (these are drugs used for GERD and peptic ulcers)
  7. Have healthy bowel (e.g. no inflammatory bowel disease) *
  8. Have bowel that will reach down to the urethra *
  9. NOT be at high risk for cancer recurrence in the pelvis *
  10. NOT have cancer at the urethral margin *

* Some things are ultimately determined during the surgery. A small fraction of patients who are candidates for a Studer pouch based on pre-operative assessment are found to have reasons why they should not have a Studer pouch during the surgery. As a result, you must be prepared to wake up with an ileal conduit after surgery even though the plan was for a Studer pouch.

 

How a Studer Pouch is Constructed

 

A Studer pouch is constructed by taking a longer segment (about 50-55 cm) of small bowel from the ileum.  That segment of bowel forms the pouch. Continuity in the bowel is re-established by sewing or stapling the cut ends back together. The isolated segment of bowel is partially opened to create long rectangular sheet which is then folded a couple of times and sewn into a pouch. The ureters are 'plugged in' to the conduit by seweing them in. Stents (essentially, specialized straws/tubes) are placed through anasstomosis (the 'joint') to allow them to heal. The stents are usually removed about 1 week after surgery. The pouch is then hand sewn into the urethra to form an anastomosis. A urethral catheter is placed through the anastomosis. There are multiple 'joins' (anastomoses) - bowel-to-bowel, ureters-to-pouch (x2) and pouch-to-urethra.

 

Studer Small

 

Care of the Studer Pouch

 

A Studer pouch is NOT a bladder. It is a bladder substitute.

 

Read the following to understand what is involved in its care. In deciding to have a Studer pouch you are consenting to life-long surveillance and maintenance which is much more involved than a conduit to the skin.

 

When a Studer pouch is working well, it can reasonably replicate what you have with your own bladder - an ability to empty into a toilet through the urethra without any external appliances or bags. Most patients do not need to catheterize and even if you do you will not require an external appliance or bag. The need for additional corrective surgery is higher with a Studer pouch. Up to 30% of patients require further surgical intervention (sometimes minor, but sometimes major).  All types of urinary reconstruction require some maintenance, just like a car. A comparison to a car was used for the ileal conduit - which is most like a Toyota/Honda - simple and (mainly) reliable. The car equivament of a Studer pouch is more like a Jaguar - it will drive wonderfully when working but it requires more scheduled and unscheduled service and the service may, at times, be very expensive. A Studer pouch requires more maintenence and participation of the patient than an conduit.

 

If after reading everything below you feel that this will be too much work, go with the Toyota (ileal conduit), not the Jaguar (Studer pouch). 

 

 

 

Cautions

Seek medical attention (Surgeon, Family Doctor or Emergency Department) if you have any of the following:

  • Your pain gets worse or does not go away with pain medication
  • You have a fever over 38.5 C (101 F)
  • Your incision becomes red, swollen, or hot to touch
  • You notice alot of clear liqud or foul smelling liquid coming from your incision
  • You start bleeding from your incision
  • You feel sick to your stomach (nauseated) or throw up (vomit) often for more than 24 hours
  • You have diarrhea that lasts for more than 2 days
  • If you have a drain that is accidentally pulled out

 

If you are not able to contact your surgeon or family doctor, go to the Emergency Department (Ideally at the hospital where your surgery was done), or call HealthLink BC at 8-1-1 to talk to a registered nurse. 

 

Diet

It might take some time before your appetite returns to normal. To heal, your body will need extra calories, nutrients, and especially protein.

  • Drink at least 6-8 glasses (2 L) of water each day (1 glass equals 250 mL or 1/4 of a litre)
  • Eat foods high in protein such as chicken, beef, eggs, tofu, lentils, dried peas, and beans. Dairy products such as mild, yogurt and cheese are also good sources of protein.
  • Try to eat 5 or 6 small meals throughout the day rather than 3 big meals.
  • If you are not able to eat enough food each day, you can continue to dring 1 or 2 oral nutrition supplement drinks (e.g. Boost or Ensure) each day.

Caring for your Bowels

Your bowels may not work the same way as they did before your surgery. It may take a few weeks for your bowels to work normally. How to treat constipation:

  • This can be from your pain medication, especially opioids.
  • Prevention:
    • Drink at least 6-8 glasses of water each day
    • Include fruits, vegetables, dried peas, beans, lentils and whole grains in your diet. These foods are high in feibre.
    • Keep active. Go for a walk every day.
  • To treat constipation, talk to your pharmacist about a mild laxative or stool softener.

Activity

Rest is important for your recovery. Try to get at least 8 hours sleep each night. Take naps or rest breaks during the day. Most patients will take 6 weeks off of work following surgery and return to work is often graded for up to 3 months if you do physical activity at work.

 

On the Web

American Cancer Society Information on Bladder Cancer

Radical Cystectomy for Muslce-invasive Bladder Cancer

Nightengale Medical Supplies Ltd.